About time pubs/devs woke up and got rid of the protection, now we'll know if it was the securom or crappy coding that was causing problems
If you want to make a NoDVD for the v1.20 patch, just Hex Edit the following byte in the Titan Quest.exe:
Offset 0x000089A7 change byte 74 to EB
Alternatively, search for byte pattern 74 7F FF and change the first byte to EB so it reads EB 7F FF!