What original disk are you using to boot your DVD-R games with?. Try using DMC demo that comes with Resident Code:Veronica, not the Platinum version as this has a very high TOC size. Also, try cleaning your laser and use a good brand of DVD-R disk, i.e. 'Verbatim'. You say you have a Neo 2.2 and a V3 PS2, the V3 has a weak laser compared to the later models that are available now, and the Neo chip will eventually burn out your laser in time as they are crap. I suggest that you get a direct boot chip if you have the cash.
